Case highlights cranial venous outflow insufficiency in stroke and headache assessment, suggesting further diagnosis.
To highlight the importance of cranial venous outflow insufficiency in assessing the etiology of strokes and headaches. This condition is commonly overlooked, and further workup with diagnostic imaging is often deferred as radiology reports do not usually comment on possible cerebral venous abnormalities. This is a unique case of a young stroke patient who required Tenecteplase (TNK) additionally presenting with chronic headaches, which subsided after venous angioplasty. To the author’s knowledge, there are no other cases reported with this specific presentation.
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Tran et al. (2026) studied this question.
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