Intra-nasal Seletracetam for Reading Epilepsy: A First in Human Proof-of-concept Case Study (P5-11.001)

June 9, 2026Neurology

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Key Points

The aim is to assess whether intranasal seletracetam can prevent seizures in a patient with drug-resistant reflex epilepsy.
Conducted a proof-of-concept case study.
Administered intranasal seletracetam to a single patient.
Monitored seizure activity before and after treatment.
Intranasal seletracetam treatment led to a significant reduction in seizure frequency.
Supportive evidence suggests efficacy against drug-resistant reflex epilepsy.
Case study provides initial insights into treatment potential.

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Case study determines that intranasal seletracetam prevents seizures in a patient with drug-resistant epilepsy, suggesting a potential treatment.

To determine if intranasal seletracetam treatment prevents seizures in a patient drug resistant reflex epilepsy.

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Klein et al. (2026) studied this question.

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