Examines brain connectivity changes in ALS, suggesting implications for understanding neurodegeneration.
Amyotrophic lateral sclerosis (ALS) is increasingly recognized as a network-level neurodegenerative disease involving distributed disruptions across structural and functional systems. While previous studies have often examined white matter integrity or functional connectivity in isolation, the nature of structure–function coupling and its reorganization in ALS remains poorly understood.
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Renga et al. (2026) studied this question.
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