Genetic Influences on Long-term CSF and Plasma Biomarker Stability in People With HIV (S22.002)

June 9, 2026Neurology

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Key Points

This study aims to determine if host genetic variants affect the long-term stability of various biomarkers in individuals with HIV.
Evaluated host genetic variants in relation to biomarkers over a 12-year period.
Assessed inflammatory, oxidative, and neurodegenerative biomarkers in the cohort.
Analyzed data to identify correlations between genetics and biomarker stability.
Certain genetic variants were associated with more stable inflammatory biomarkers over the period.
Findings suggest a link between genetic factors and the long-term consistency of oxidative and neurodegenerative biomarkers.

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Investigates genetic effects on biomarker stability in people with HIV, suggesting significant influences.

To investigate whether host genetic variants influence 12-year stability of inflammatory, oxidative, and neurodegenerative biomarkers in PWH.

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Lima et al. (2026) studied this question.

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