Parkinson’s Disease: Increased Presence of Neuropsychiatric Symptoms and Non-motor Issues Drive Higher Medication Use and Costs (P5-16.014)

Sarah Horn; Okeanis Vaou; Ashwini Parab; Siting Wang; Xing Pan; Connie Yan; Megha Shah; Joohi Jimenez‐Shahed

doi:10.1212/wnl.0000000000215531

June 9, 2026Neurology

Parkinson’s Disease: Increased Presence of Neuropsychiatric Symptoms and Non-motor Issues Drive Higher Medication Use and Costs (P5-16.014)

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Key Points

The research aims to compare medication use and costs related to neuropsychiatric disorders and other non-motor symptoms in advanced Parkinson's Disease against newly diagnosed individuals and those without the disease.
Included aPD, newly diagnosed PD, and no-PD groups for comparison
Analyzed differences in neuropsychiatric disorders, non-motor symptoms, and associated medication use
Examined healthcare costs related to medication across the groups
Individuals with advanced Parkinson's Disease showed significantly higher medication use compared to newly diagnosed and no-PD groups
Increased presence of neuropsychiatric symptoms was linked to higher overall healthcare costs
Non-motor issues contributed significantly to medication expenses in advanced Parkinson's Disease patients

Implication

Comparison reveals higher medication use and costs due to neuropsychiatric and non-motor symptoms in advanced Parkinson’s Disease versus newly diagnosed individuals and controls, suggesting...

Abstract

Compare neuropsychiatric disorders (NPsy), other non-motor symptoms (NMS), and associated medication use and costs in advanced Parkinson’s Disease (aPD) with individuals newly diagnosed with PD (PD) and without PD (no-PD).

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Cite This Study

Horn et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf393faef96ed7f056118 https://doi.org/10.1212/wnl.0000000000215531

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Parkinson’s Disease: Increased Presence of Neuropsychiatric Symptoms and Non-motor Issues Drive Higher Medication Use and Costs (P5-16.014)

Key Points

Implication

Abstract

Discussion

Cite This Study

Parkinson’s Disease: Increased Presence of Neuropsychiatric Symptoms and Non-motor Issues Drive Higher Medication Use and Costs (P5-16.014)

Key Points

Implication

Abstract

Discussion

Cite This Study

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