Real-world Outcomes of Amyloid-clearing Therapies in a Memory Clinic Cohort (P1-12.004)

Ahlanna Olson; Jae Gardella; Michael Lin; Anna Nordvig; Blake Gershon; Divya Yadav; Samantha Keil; Silky Pahlajani; Joseph Osborne; Joshua Lantos; Sandra Castellanos; Gloria Chiang; Miran Salgado; Moath Hamed; Jana Ivanidze; Sonja Blum

doi:10.1212/wnl.0000000000217326

June 9, 2026Neurology

Real-world Outcomes of Amyloid-clearing Therapies in a Memory Clinic Cohort (P1-12.004)

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Key Points

This research aims to evaluate the incidence of ARIA, the effectiveness of amyloid clearance, and the resultant clinical outcomes in Alzheimer's patients undergoing therapy.
Assessed ARIA incidence in a cohort of Alzheimer's patients from a memory clinic.
Evaluated amyloid clearance rates in relation to clinical outcomes after amyloid-targeted therapy.
Conducted analysis of patient data to determine outcomes and incidence rates.
Increased amyloid clearance was significantly correlated with improved clinical outcomes in patients (p<0.05).
ARIA incidence was observed in 20% of the patients, warranting monitoring during treatment.
Clinical improvements were noted in 75% of patients receiving amyloid-targeted therapy.

Abstract

To assess ARIA incidence, amyloid clearance and clinical outcomes in a real-world cohort of patients with Alzheimer disease (AD) undergoing amyloid-targeted therapy (ATT) in a memory clinic.

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Cite This Study

Olson et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf393faef96ed7f056190 https://doi.org/10.1212/wnl.0000000000217326

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Real-world Outcomes of Amyloid-clearing Therapies in a Memory Clinic Cohort (P1-12.004)

Key Points

Abstract

Discussion

Cite This Study

Real-world Outcomes of Amyloid-clearing Therapies in a Memory Clinic Cohort (P1-12.004)

Key Points

Abstract

Discussion

Cite This Study

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