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Case report reveals severe visual loss and elevated intracranial pressure leading to CBS.
Glial fibrillary acidic protein (GFAP) autoimmune astrocytopathy has been associated with optic perineuritis and papillitis, typically with normal intracranial pressure and visual sparing. We describe a case of multiphasic GFAP astrocytopathy marked by severe visual loss and elevated intracranial pressure (EICP) requiring ventriculoperitoneal shunting (VPS), with later emergence of Charles Bonnet Syndrome (CBS).
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Iskandarian et al. (2026) studied this question.
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