What question did this study set out to answer?

This case aims to describe the occurrence of AQP4-IgG–positive neuromyelitis optica spectrum disorder (NMOSD) in the setting of dual malignancies.

June 13, 2026Neurology

Paraneoplastic Neuromyelitis Optica Spectrum Disorder Associated with Dual Malignancies: Rectal Adenocarcinoma and Lung Carcinoid Tumor (P1-2.002)

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This case aims to describe the occurrence of AQP4-IgG–positive neuromyelitis optica spectrum disorder (NMOSD) in the setting of dual malignancies.
Described a unique case involving a patient with metastatic rectal adenocarcinoma and lung carcinoid tumor.
Presented clinical and literature context regarding paraneoplastic NMOSD cases.
Identified AQP4-IgG positivity in the patient with dual malignancies.
Contextualized the unusual case within existing literature on paraneoplastic NMOSD.

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Implication

Case report describes a unique presentation of NMOSD linked to rectal adenocarcinoma and lung carcinoid tumor, suggesting further investigation into paraneoplastic associations.

Cite This Study

Kus et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3d6faef96ed7f0563ee https://doi.org/10.1212/wnl.0000000000216537

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Implication

Case report describes a unique presentation of NMOSD linked to rectal adenocarcinoma and lung carcinoid tumor, suggesting further investigation into paraneoplastic associations.

Paraneoplastic Neuromyelitis Optica Spectrum Disorder Associated with Dual Malignancies: Rectal Adenocarcinoma and Lung Carcinoid Tumor (P1-2.002)

Key Points

Discussion

Implication

Cite This Study

Paraneoplastic Neuromyelitis Optica Spectrum Disorder Associated with Dual Malignancies: Rectal Adenocarcinoma and Lung Carcinoid Tumor (P1-2.002)

Key Points

Discussion

Implication

Cite This Study

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