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June 9, 2026Neurology

A Rare Case of Chronic Lymphocytic Inflammation with Perivascular Enhancement Responsive to Steroids in Both Pontine and Supratentorial Region (P8-2.014)

Durgesh Chaudhary Aatqa Memon Xiao (Sharon) Wei Jikku Jose Zachariah Yohance Allette

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Key Points

To describe a rare case of chronic lymphocytic inflammation with specific regional characteristics and treatment response.
Case report detailing clinical presentation and imaging findings in affected brain regions.
Assessment of steroid treatment efficacy in managing inflammation in pontine and supratentorial areas.
Inflammation in both the pontine and supratentorial regions showed notable reduction following steroid therapy, indicating treatment effectiveness.
Clinical symptoms improved significantly post-intervention, highlighting the utility of steroids in similar cases.

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Implication

Case report reveals steroid responsiveness in chronic lymphocytic inflammation affecting brain areas, suggesting a potential treatment approach.

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Cite This Study

Chaudhary et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3d6faef96ed7f0564e4 https://doi.org/10.1212/wnl.0000000000217435

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5Monoclonal Gammopathy of Neurological Significance in a Patient With Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS Syndrome): A Case Report of a Rare Entity2024