Multiple Sclerosis Disease Activity is Uncommon in Individuals With Pre-existing Multiple Sclerosis Exposed to Immune Checkpoint Inhibitor Therapy (P4-19.002)

Alexander Gill; Jonathan Krett; Carson Quinn; Prashanth Rajarajan; Lyndsey Babcock; Anna Kaiser; Andrew Morrison; Thomas Pisano; Atika Paracha; Cory Dodson; Hannah Kopinsky; Iwalewa Moninuola; Said Alhassan; Wendy Stewart; Maria Aguilera-Pena; Sofia Ramierz Guerrero; Nikhil Modak; Maxime Jean; Jessica Lamb; Yoav Piura; Jordan CARRIER; Muhammed Ikbal Arvas; Celeste Camargo; Vikram Bhise; Jenny Linnoila; Vinay Chaudhry; Shamik Bhattacharyya; E Alvarez; Daniel Kantor; Flavia Nelsion; Kottil Rammohan; Patricia Coyle; Lauryn Hemminger; Nicole Baldwin; George Hutton; Alexandra Simpson; Paula Barreras; Irena Dujmovic Basuroski; Cole Harrington; Anne Douglas; Gregory Day; Ilya Kister; Kristin Galetta; Sarah Conway; Shuvro Roy; Sachin Gadani; Andrew Wolf; John Probasco

doi:10.1212/wnl.0000000000213057

June 9, 2026Neurology

Multiple Sclerosis Disease Activity is Uncommon in Individuals With Pre-existing Multiple Sclerosis Exposed to Immune Checkpoint Inhibitor Therapy (P4-19.002)

View at Publisher

Ask AI

Bookmark

Share

Key Points

This research aims to determine the neurologic outcomes for individuals with multiple sclerosis exposed to immune checkpoint inhibitors.
Participants included individuals with pre-existing multiple sclerosis.
Exposure to immune checkpoint inhibitors was evaluated for comorbid oncologic indications.
Disease activity was uncommon in the cohort following ICI therapy.
No significant exacerbations were reported during the follow-up period.

Implication

Examines neurologic outcomes after immune checkpoint inhibitor therapy in individuals with multiple sclerosis, suggesting low disease activity rates.

Abstract

To determine neurologic outcomes in people with multiple sclerosis (pwMS) after exposure to immune checkpoint inhibitors (ICIs) for comorbid oncologic indications.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Gill et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf403faef96ed7f05662a https://doi.org/10.1212/wnl.0000000000213057

View at Publisher

Ask AI

Bookmark

Share

Multiple Sclerosis Disease Activity is Uncommon in Individuals With Pre-existing Multiple Sclerosis Exposed to Immune Checkpoint Inhibitor Therapy (P4-19.002)

Key Points

Implication

Abstract

Discussion

Cite This Study

Multiple Sclerosis Disease Activity is Uncommon in Individuals With Pre-existing Multiple Sclerosis Exposed to Immune Checkpoint Inhibitor Therapy (P4-19.002)

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

More related papers

More from Neurology

Keep reading

More related papers

More from Neurology