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June 13, 2026Aquaculture NutritionOpen Access

Compensatory Fatty Acid Metabolism and Hepatic Gene Expression in African Catfish ( Clarias gariepinus ) Fed Marine‐Ingredient‐Free Circular Diets Low in EPA and DHA

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Authors

CSChristopher ShawKKKlaus KnopfSWSven Wuertz

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Overview

Randomized trial evaluates fatty acid profiles and gene expression in African catfish, suggesting diet formulation potential.

Key Points

  • The study investigates how low levels of EPA and DHA in diets affect growth, fatty acid profiles, and gene expression in African catfish.
  • Tested different diets replacing salmon oil with rapeseed oil in the formulation.
  • Evaluated growth performance, liver and fillet fatty acid profiles, and gene expression dynamics (elovl2, elovl5, fads2).
  • Assessed nutrient excretion compared to a commercial control diet.
  • Growth performance did not match the commercial diet, but low EPA + DHA levels did not negatively affect growth.
  • Significantly elevated expression of elovl2, elovl5, and fads2 in rapeseed oil-fed fish.
  • Fillet EPA + DHA content and n-6:n-3 ratio significantly declined compared to salmon oil diets.

Cite This Study

Shaw et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf528faef96ed7f05735dhttps://doi.org/10.1155/anu/4162985
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