Exciting and Emerging Advances in Peroxisome Biology

Since the first report of peroxisomes as distinct “microbodies” in the proximal tubule cells of mouse kidney (Rhodin, 1954) and their biochemical identification as sites of hydrogen peroxide (H₂O₂) production and degradation (De Duve and Baudhuin, 1966), the peroxisome field has burgeoned from a small number of publications (<100/year) from a few laboratories to >2500/year from many investigators today. What follows is a historical perspective on the exciting and emerging advances in peroxisome biology over the past 70 years.