Comprehensive review evaluates TCM's role in enhancing reproduction efficiency in animals, suggesting pathways for application.
Key Points
This review aims to evaluate the therapeutic potential of Traditional Chinese Medicine (TCM) in enhancing animal reproductive efficiency and identify translational barriers.
Systematic evaluation of literature from PubMed, Web of Science, and CNKI up to October 2025.
Classification of fifteen medicinal plants into tonifying, blood-activating, and heat-clearing categories.
Summarization of bioactive compounds, target tissues, and signalling pathways in structured tables.
Identified conserved regulatory networks including PI3K/Akt, Nrf2/HO-1, NF-κB, and AMPK/SIRT1 that modulate the hypothalamic-pituitary-gonadal axis.
TCM compounds mitigate oxidative and inflammatory stress, improving reproductive organ function across species.
Challenges include dosage re-determination for species differences, standardization, and scarce large-scale clinical trials.