Key result
Prophylactic LMWH cuts DVT, thromboembolism, or death ~72% vs compression stockings.
Authors
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RCT (n=1,761)
Assessor-blind
randomly assigned
Yes
Absolute Risk Reduction: 2.3 (95% CI 0.7–4)
Absolute Event Rate: 0.9% vs 3.2%
Absolute Risk Reduction: 2.3%
p-value: p=0.005
Camporese et al. (2008) conducted an RCT in Knee arthroscopy (n=1,761). Low-molecular-weight heparin (LMWH) vs. Full-length graduated compression stockings was evaluated on Combined incidence of asymptomatic proximal deep venous thrombosis, symptomatic venous thromboembolism, and all-cause mortality (absolute difference 2.3 percentage points, 95% CI 0.7 to 4.0 percentage points, p=0.005). Prophylactic low-molecular-weight heparin for 1 week reduced deep venous thrombosis, thromboembolism, or death compared with compression stockings (0.9% vs 3.2%; P=0.005).
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