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June 15, 2026Rinsho ShinkeigakuOpen Access

Anti-NF155 antibody-positive autoimmune nodopathy with myocardial 123I-MIBG scintigraphy abnormality

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Authors

SKSuguru KadowakiAMAkeshi MorimatsuASAkiko Shirata

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Overview

Case report shows autoimmune nodopathy affecting small fibers in a patient with CIDP, indicating significant testing implications.

Key Points

  • This report aims to detail the clinical presentation and diagnosis of anti-NF155 antibody-positive autoimmune nodopathy.
  • Clinical examination of a 68-year-old man with neurological symptoms.
  • Nerve conduction studies and cerebrospinal fluid analysis were performed.
  • Contrast-enhanced MRI neurography and myocardial scintigraphy were conducted to evaluate nerve root involvement.
  • Patient exhibited demyelinating abnormalities in nerve conduction studies.
  • Initial IVIg treatment was ineffective, while corticosteroids had mild effects.
  • Positive anti-NF155-IgG antibodies confirmed the diagnosis of autoimmune nodopathy.

Cite This Study

Kadowaki et al. (2026) studied this question.

synapsesocial.com/papers/6a2f966ca1cfeec490827e59https://doi.org/10.5692/clinicalneurol.cn-002212
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