ABSTRACT Background and Aims In the ever‐evolving domain of healthcare, Decision Support Systems (DSS) stand at the forefront of technological advancement, promising to revolutionize patient care. This systematic review investigated the factors that influence the adoption of DSS, and provides important insights into their use in healthcare services. Methods Using the PRISMA framework, this systematic review was conducted based on articles published in the time frame of 2000–2024. A systematic literature search was conducted across PubMed, Scopus, ProQuest, and the Cochrane Library. The AACODS checklist was used for quality assessment of the included studies. Subsequently, a thematic analysis was conducted on the acquired data. Results Eighty‐six studies were included in the research. The included studies were deemed to bear high quality and low risk of bias. The research illuminated 11 themes and 47 sub‐themes. The themes included system design and integration, user characteristics, personalization, trust, quality, utility, satisfaction and acceptability, education and awareness, involvement, settings, and ethical‐legal issues. Conclusion The study yielded comprehensive data that addressed the research questions by presenting an extensive list of factors influencing the utilization of DSS in healthcare. The perceived importance of these factors varied, as indicated by the differing frequencies with which they were cited across the included studies. This disparity in factor importance was particularly pronounced when comparing developed and developing countries.
Khosravi et al. (Mon,) studied this question.