June 15, 2026Open Access
View Full PaperFunctional Measurement of Coronary Stenosis
Key Result
Fractional flow reserve is the gold standard for invasive assessment of physiologic stenosis significance and improves outcomes in most elective clinical and angiographic conditions.
Key Points
- This paper aims to analyze the role of fractional flow reserve (FFR) in evaluating the significance of coronary stenosis.
- Discusses the application and characteristics of FFR in various patient subsets.
- Reviews the guidelines for FFR use in multivessel percutaneous coronary intervention.
- Explores the practical aspects of using FFR in catheterization laboratories.
- FFR is considered the gold standard for assessing physiologic significance of coronary stenosis.
- Accurate identification of lesions benefiting from stenting can improve outcomes in elective cases.
- FFR has been upgraded to a class IA recommendation in new European guidelines.
Structured PICO
P
Population
Patients undergoing invasive assessment of coronary stenosis significance
I
Intervention
Fractional flow reserve (FFR)
FFR is an indispensable tool for decision making in coronary revascularization, recently upgraded to a class IA classification in ESC guidelines.
Abstract
Fractional flow reserve (FFR) is considered nowadays as the gold standard for invasive assessment of physiologic stenosis significance and an indispensable tool for decision making in coronary revascularization. Use of FFR in the catheterization laboratory accurately identifies which lesions should be stented and improves the outcome in most elective clinical and angiographic conditions. Recently, FFR has been upgraded to a class IA classification in multivessel percutaneous coronary intervention in the guidelines on coronary revascularization of the European Society of Cardiology. In this state-of-the-art paper, the basic concept of FFR and its application, characteristics, and use in several subsets of patients are discussed from a practical point of view. (J Am Coll Cardiol 2012;59:1045-57) (C) 2012 by the American College of Cardiology Foundation Original language English Pages (from-to) 1045-1057 Journal Journal of the American College of Cardiology Volume 59 Issue number 12 DOIs https://doi.org/10.1016/j.jacc.2011.09.077 Publication status Published - 2012
Cite This Study
Pijls et al. (Thu,) conducted a review in Coronary stenosis. Fractional flow reserve (FFR) was evaluated. Fractional flow reserve is the gold standard for invasive assessment of physiologic stenosis significance and improves outcomes in most elective clinical and angiographic conditions.