Higher ASA physical status was independently associated with poorer preoperative health-related quality of life (FACT-C total score B = -5.05; 95% CI -9.70 to -0.40; p=0.033).
Cross-Sectional
Preoperative HRQoL in elective colorectal cancer surgery patients is moderate, does not differ by tumor location, and is negatively impacted by higher ASA physical status.
Effect estimate: B -5.05 (95% CI -9.70 to -0.40)
p-value: p=0.033
Introduction: Health-related quality of life (HRQoL) is an important multidimensional, patient-centered concept in colorectal cancer (CRC). However, data on preoperative HRQoL in Southeast European surgical populations remain limited. This study aimed to describe preoperative HRQoL in patients undergoing elective surgery for CRC, compare HRQoL between colon and rectal cancer, and identify sociodemographic and clinical factors associated with preoperative HRQoL. Material and Methods: Preoperative HRQoL was assessed using the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) and the Cleveland Clinic Colorectal Cancer Quality of Life questionnaire (CCF-CaQL). Sociodemographic and clinical data were collected using a structured questionnaire and medical records. Group comparisons were performed by tumor localization, and factors associated with the FACT-C total score were evaluated using univariable and multivariable linear regression. Results: The mean CCF-CaQL total score was 92.3±20.4, and the mean FACT-C total score was 98.8±18.2. No significant differences in HRQoL were observed between patients with colon or rectal cancer across any questionnaire domains (all p 0.05). In multivariable analysis, higher ASA physical status was independently associated with a lower FACT-C total score (B = -5.05; 95% CI = -9.70 to -0.40; p = 0.033). Conclusion: Preoperative HRQoL in patients undergoing elective CRC surgery was moderate and did not differ significantly by tumor localization. Higher ASA physical status was independently associated with poorer preoperative HRQoL.
Nikolić et al. (Thu,) conducted a cross-sectional in Colorectal cancer. Higher ASA physical status vs. Lower ASA physical status was evaluated on FACT-C total score (B -5.05, 95% CI -9.70 to -0.40, p=0.033). Higher ASA physical status was independently associated with poorer preoperative health-related quality of life (FACT-C total score B = -5.05; 95% CI -9.70 to -0.40; p=0.033).
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