Key result
Precise imaging is essential to accurately diagnose and risk-stratify rare single coronary artery anomalies.
Why the study?
Single coronary artery is a rare congenital coronary anomaly that can pose a serious threat to health, requiring a thorough understanding of anatomical and clinical characteristics for accurate diagnosis and risk assessment.
This comprehensive review highlights the critical role of multimodality imaging in the precise diagnosis and risk stratification of single coronary artery anomalies.
May improve SCA diagnosis via multimodality imaging; extends classifications but leaves practice implications open.
Single coronary artery (SCA) is a rare congenital coronary anomaly. This condition may lead to myocardial ischemia, angina pectoris, and even sudden cardiac death. Generally speaking, if there are no other heart abnormalities, a SCA can be entirely asymptomatic. However, it may also pose a serious threat to health and survival. A thorough understanding of its anatomical and clinical characteristics is essential for accurate diagnosis and risk assessment. Medical imaging plays an important role in the diagnosis of a SCA. Precise imaging not only enables identification of the anomaly subtype but also allows comprehensive evaluation of coronary anatomy, myocardial perfusion, and concomitant lesions, thereby providing critical guidance for clinical decision-making. From echocardiography and conventional coronary angiography to noninvasive modalities such as computed tomography angiography and magnetic resonance angiography, each imaging technique has distinct clinical applications. Based on current literature, this review focuses on recent advances in SCA, systematically summarizing its clinical and anatomical characteristics, major classification systems, imaging diagnosis, clinical implications, and high-risk patterns, with the aim of providing a reference for precise diagnosis and therapeutic strategies.
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Zhang et al. (2026) conducted a review in Single coronary artery (SCA). Single coronary artery was evaluated. Single coronary artery is a rare congenital anomaly that requires precise imaging for accurate diagnosis, risk assessment, and clinical decision-making.
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