Key result
Iodinated contrast-induced AKI carries higher risks of renal replacement therapy, rehospitalization, and death.
This paper provides a comprehensive review of the epidemiology, pathophysiology, prognosis, and management of contrast-induced acute kidney injury in the cardiac catheterization laboratory.
Coronary angiography and percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber imaging. Despite advancements in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-induced acute kidney injury (CI-AKI) for a subgroup of patients at risk for this complication. There has been a consistent and graded signal of risk for associated outcomes including need for renal replacement therapy, rehospitalization, and death, according to the incidence and severity of CI-AKI. This paper reviews the epidemiology, pathophysiology, prognosis, and management of CI-AKI as it applies to the cardiac catheterization laboratory.
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McCullough et al. (2016) conducted a review in Contrast-induced acute kidney injury (CI-AKI). Iodinated intravascular contrast was evaluated. Iodinated intravascular contrast poses a risk of contrast-induced acute kidney injury, which is associated with increased need for renal replacement therapy, rehospitalization, and death.
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