A fluorous phase oxygen optical nanosensor for mitigating redox-active microbial metabolite interference

Key Points

• The aim is to develop a nanosensor that effectively addresses interference from redox-active microbial metabolites, particularly pyocyanin.
• Developed an oxygen-sensitive nanosensor encapsulated in a fluorous phase to reduce quenching effects.
• Assessed the lipophilicity of various microbial metabolites in different chemical conditions.
• Evaluated the effectiveness of the nanosensor in mitigating interference during measurements.
• Successfully reduced quenching effects from pyocyanin, improving sensor accuracy.
• Demonstrated enhanced sensitivity and reliability in detecting dissolved oxygen compared to traditional sensors.