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June 14, 2026New Phytologist

Dynamic regulation of the BIK1 – RIN4 complex determines plant immunity and effector‐mediated virulence

H Lee Dohee Ko Hobin Kang Eunjeong Jang Ohkmae K. Park Sang Hee Kim Farid El Kasmi Eui‐Hwan Chung

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Key Points

The study aims to understand how the dynamics of the BIK1-RIN4 protein complex affect plant immunity and virulence.
Investigated the interaction dynamics of BIK1-RIN4 protein complex during immune responses.
Conducted analyses on the implications for effector-mediated virulence in plants.
The dynamics of the BIK1-RIN4 complex significantly impact plant immune responses.
Alterations in the complex contribute to varying levels of effector-mediated virulence.

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Implication

Uncovers the influence of BIK1-RIN4 protein complex on plant immunity, suggesting new ways to enhance resistance.

Abstract

Dynamics of BIK1-RIN4 protein complex during arms race.

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Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/6a323b4cd50b63ecad205eec https://doi.org/10.1111/nph.71349

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1BIK1-RIN4 complex links plant immunity and pathogen virulence2025
2The <i>Ralstonia solanacearum</i> effector <scp>RipAV</scp> targets plant U‐box proteins and induces proteasomal‐dependent degradation of <scp>BIK1</scp>2025 · 6 citations
3Myosin XI-mediated BIK1 recruitment to nanodomains facilitates FLS2–BIK1 complex formation during innate immunity in <i>Arabidopsis</i>2024 · 13 citations
4Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunityOriginal Research · 2026 · 7 citations
5Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunityOriginal Research · 2026

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Plant immune dysregulation disrupts microbe-induced growth promotion and microbiome compatibility2026
New alleles of Arabidopsis BIK1 reinforce its predominant role in pattern-triggered immunity and caution interpretations of other reported functions2026
A fungal pathogen manipulates phytocytokine signaling for plant infection2025

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