Dupilumab demonstrates effectiveness for allergic fungal rhinosinusitis in individuals post-surgery, suggesting a new treatment option.
Dupilumab (Dupixent – Sanofi/Regeneron), a subcutaneously injected interleukin (IL)-4 receptor alpha antagonist that is FDA-approved for several indications, including treatment of chronic rhinosinusitis with nasal polyps, has now been approved for treatment of allergic fungal rhinosinusitis (AFRS) in patients ≥6 years old who previously had sinonasal surgery.1-3 It is the first drug to be approved in the US for this indication.
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