Retrospective cohort study investigates anesthesia failure in molars linked to pulp stone presence, suggesting no significant impact.
Introduction: The close relationship between pulp stones in the pulp chamber and pulp neurovascular tissues suggests that the presence of pulp stones may compromise successful anesthesia. The present study assessed the effect of pulp stone presence on the failure of anesthesia in mandibular and maxillary molars. Materials & Methods: In this retrospective cohort study, 126 patients were studied. Pulp stones were diagnosed by periapical radiography. After the anesthetic agent injection, failure was defined as patients raising their hand upon experiencing pain during any procedural step of endodontic treatment. Furthermore, sound, eye, and motor (SEM) measures were used to assess the pain experience. In the case of either pain felt or the patients' demand, supplementary injections were made using the intraligamental technique. Multivariate logistic regression analysis was used to assess the effects of different variables on the success of anesthesia. Conclusion: Pulp stones had no significant effect on the success of anesthesia in mandibular and maxillary molars.
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Parirokh et al. (2026) studied this question.
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