Triazole Salicylaldehyde-Derived Organosilane as ‘Turn-On’ Fluorescence and Colorimetric Sensor for Ce(III): Synthesis, Anticancer and Molecular Docking Studies

Gurjaspreet Singh; Poonam .; Manraj Singh; Baljinder singh Gill; Shipra Goyal; Aman Bhalla

doi:10.1039/d6nj01122e

January 1, 2026New Journal of Chemistry

Triazole Salicylaldehyde-Derived Organosilane as ‘Turn-On’ Fluorescence and Colorimetric Sensor for Ce(III): Synthesis, Anticancer and Molecular Docking Studies

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Key Points

The study aims to develop a novel organosilane chemosensor for detecting Ce(III) through fluorescence and colorimetric methods.
Synthesis of salicylaldehyde triazole-functionalized silane via copper(I)-catalyzed azide-alkyne cycloaddition.
Evaluation of the chemosensor's dual-mode response to Ce(III) ions.
Molecular docking studies to assess anticancer potential.
The synthesized organosilane exhibits significant fluorescence enhancement and color change in the presence of Ce(III) ions.
Molecular docking studies reveal promising interactions with cancer-related targets.
The dual-mode sensor indicates potential for practical applications in environmental and biomedical fields.

Implication

Demonstrates a new chemosensor for Ce(III) in dual-mode applications, indicating potential in anticancer studies.

Abstract

In the present investigation, a derivative salicylaldehyde triazole-functionalized silane (SS) was synthesized using a copper(I) -catalysed azide -alkyne cycloaddition (CuAAC) technique. The synthesized organosilane effective dual-mode chemosensor, enabling naked-eye colorimetric...

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Cite This Study

Singh et al. (2026) studied this question.

synapsesocial.com/papers/6a323e36d50b63ecad2078fd https://doi.org/10.1039/d6nj01122e

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Triazole Salicylaldehyde-Derived Organosilane as ‘Turn-On’ Fluorescence and Colorimetric Sensor for Ce(III): Synthesis, Anticancer and Molecular Docking Studies

Key Points

Implication

Abstract

Discussion

Cite This Study

Triazole Salicylaldehyde-Derived Organosilane as ‘Turn-On’ Fluorescence and Colorimetric Sensor for Ce(III): Synthesis, Anticancer and Molecular Docking Studies

Key Points

Implication

Abstract

Discussion

Cite This Study

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