Study of seroprevalence of toxoplasma in bad obstetric history

Background: The occurrence of fetal death poses a significant challenge for obstetric care providers. Viruses are the primary concern, followed by bacteria and protozoa associated with infections during pregnancy. Among protozoal infections, toxoplasmosis is reported to have a high incidence and is one of the pivotal reasons for fetal mortality. Thereby, the present analysis aims to investigate the prevalence of toxoplasmosis among pregnant women experiencing a bad obstetric history. Methodology: The current investigation was a prospective study carried out in the Department of Microbiology over a period of 1 year and 6 months. In this study, overall 120 patients were included. Venous blood was collected from the patients, labeled, and centrifuged at 3000 rpm for 10 min. Two tests were performed for the detection of T. gondii, i.e., NovaLisa Toxoplasma gondii IgM U-capture and NovaLisa T. gondii IgG tests. Results: In the current investigation, the seroprevalence of IgM and IgG antibodies was observed as 5% and 45%, respectively. Total seroprevalence toxoplasmosis was found to be around 51.7%. A higher incidence of seropositive cases of toxoplasmosis was linked to a nonvegetarian diet when compared to a vegetarian diet. Conclusion: Seroprevalence of toxoplasmosis was found to be 51.7% which indicates that, T. gondii infection has an important role in the adverse fetal outcome in pregnant women.