What question did this study set out to answer?

The study aims to evaluate the feasibility of hybrid gallium 68-FAPI-4 PET/MRI for imaging in dilated cardiomyopathy.

June 17, 2026Radiology0 citations

Hybrid Cardiac 68 Ga-FAPI-4 PET/MRI in Dilated Cardiomyopathy: A Feasibility and Pilot Study

YZYaqiong ZhouFirst Affiliated Hospital of Chengdu Medical College LHLin HuaSichuan University CHChuan HuangSichuan University

Key Result

Hybrid cardiac 68Ga-FAPI-4 PET/MRI successfully enabled simultaneous molecular and structural imaging for nonischemic dilated cardiomyopathy.

Key Points

The study aims to evaluate the feasibility of hybrid gallium 68-FAPI-4 PET/MRI for imaging in dilated cardiomyopathy.
Conducted a pilot study using gallium 68-labeled fibroblast activation protein inhibitor-4 for imaging.
Employed PET/MRI technology to assess both molecular and structural cardiac features.
Successfully demonstrated simultaneous molecular and structural imaging.
Showed effective imaging capabilities in identifying nonischemic dilated cardiomyopathy.

Structured PICO

Does Hybrid Cardiac 68Ga-FAPI-4 PET/MRI enable simultaneous molecular and structural imaging in patients with nonischemic dilated cardiomyopathy?

Population

Patients with nonischemic dilated cardiomyopathy

Intervention

Hybrid Cardiac 68Ga-FAPI-4 PET/MRI

Outcome

Feasibility of simultaneous molecular and structural imagingsurrogate

Hybrid 68Ga-FAPI-4 PET/MRI is a feasible modality for simultaneous molecular and structural imaging in nonischemic dilated cardiomyopathy.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Cardiac gallium 68–labeled fibroblast activation protein inhibitor-4 PET/MRI successfully enabled simultaneous molecular and structural imaging for nonischemic dilated cardiomyopathy.

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