Jianpi Qingre Tongluo prescription (Huangqin Qingre Chubi capsule) protects the self-perception of patients with gouty arthritis through neutrophil to lymphocyte ratio: A nested case-control study

Figures

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  Figure 1.. Study flow chart. GA = gouty arthritis, ICD = International Classification of Diseases, HQC = Huangqin Qingre Chubi capsule, SPP = self-perception of patients, SF-36 = the MOS 36-Item Short-Form Health Survey, VAS = visual analog scale, SAS = self-rating anxiety scale, SDS = self-rating depression scale, SDH = syndrome of dampness-heat quantitative score, SDSSD = syndrome of dampness stagnancy due to spleen deficiency quantitative score, SBS = syndrome of blood stasis quantitative score, NLR = neutrophil to lymphocyte ratio, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, UA = uric acid.

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  Figure 2.. Schematic diagram of mediation analysis. Note: X represents the independent variable, M represents the mediating variable, and Y represents the dependent variable. HQC = Huangqin Qingre Chubi capsule, NLR = neutrophil to lymphocyte ratio, SPP = self-perception of patients, PF = physical functioning, RP = role physical, BP = bodily pain, GH = general health, VT = vitality, SF = social functioning, RE = role emotional, MH = mental health, HT = health transition, VAS = visual analog scale, SAS = self-rating anxiety scale, SDS = self-rating depression scale, SDH = syndrome of dampness-heat quantitative score, SDSSD = syndrome of dampness stagnancy due to spleen deficiency quantitative score, SBS = syndrome of blood stasis quantitative score.

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  Figure 3.. Forest plot of risk factors for SPP. (A) Forest plot for PF; (B) Forest plot for VAS; (C) Forest plot for SDS; (D) Forest plot for SDH; (E) Forest plot for SDSSD; (F) Forest plot for SBS. SPP = self-perception of patients, HQC = Huangqin Qingre Chubi capsule, NLR = neutrophil to lymphocyte ratio, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, UA = uric acid, PF = physical functioning, VAS = visual analog scale, SDS = self-rating depression scale, SDH = syndrome of dampness-heat quantitative score, SDSSD = syndrome of dampness stagnancy due to spleen deficiency quantitative score, SBS = syndrome of blood stasis quantitative score.

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  Figure 4.. Network diagram of association rules for HQC and indexs. Note: Circles represent terms, and darker colors represent terms that occur more often. The line represents the association between 2 items, and the thicker line and darker color represent the stronger association between the 2 items. HQC = Huangqin Qingre Chubi capsule, NLR = neutrophil to lymphocyte ratio, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, UA = uric acid, PF = physical functioning, RP = role physical, BP = bodily pain, GH = general health, VT = vitality, SF = social functioning, RE = role emotional, MH = mental health, HT = health transition, VAS = visual analog scale, SAS = self-rating anxiety scale, SDS = self-rating depression scale, SDH = syndrome of dampness-heat quantitative score, SDSSD = syndrome of dampness stagnancy due to spleen deficiency quantitative score, SBS = syndrome of blood stasis quantitative score.