⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

June 15, 2026Chemical Research in Toxicology

Multiparametric and Pathomimetic In Vitro Platform Mimicking Human Hepatic Steatosis, Lipotoxicity, and Associated Metabolic Stress

Jyoti Sharma Priyankar Dey

View at Publisher

Ask AI

Bookmark

Share

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Abstract

model for MASLD, suitable for therapeutic screening and mechanistic research.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/6a338a8f630953a74978c9fc https://doi.org/10.1021/acs.chemrestox.6c00049

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived AssaysReview · 2025 · 9 citations
2Comparison of wild-type and high-risk PNPLA3 variants in a human biomimetic liver microphysiology system for metabolic dysfunction-associated steatotic liver disease precision therapy2024 · 16 citations
3The HepG2 Cell Line as a Model for Studying Metabolic Dysfunction-Associated Steatotic Liver DiseaseReview · 2026 · 7 citations
4Preclinical Models of Metabolic Dysfunction–Associated Steatotic Liver Disease for Therapeutic TestingHuman Clinical Trial · 2026
5Hepatocyte Models for Metabolic Dysfunction-Associated Steatotic Liver Disease: A Comparative Analysis of Non-HepG2 Cell ModelsReview · 2026 · 1 citations

Metabolic Dysfunction-Associated Steatotic Liver Disease in a Dish: Human Precision-Cut Liver Slices as a Platform for Drug Screening and Interventions2024
Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease2024
Human skin stem cell-derived hepatic cells as in vitro drug discovery model for insulin-driven de novo lipogenesis2023
Immunomodulatory, Genotoxic, and Antiestrogenic Properties of the Alternaria Mycotoxins Tricycloalternarene 2b and Tricycloalternarene 3aChemical Research in Toxicology · 2026
PFOS Is Detected in Human Pancreas and Dysregulates Glucose-Stimulated Insulin Secretion across Model SystemsChemical Research in Toxicology · 2026

More from Chemical Research in Toxicology

More from Thapar Institute of Engineering & Technology