Assessment of Laparoscopic Nissen Fundoplication Procedure on Patients’ Quality of Life: A Hospital-based Interventional Study

ultimately impacting the physical, mental, and social well-being.This in turn reduces productivity and affects the socioeconomic status of patients and their families. 8he management of GERD follows a holistic, stepwise approach.The goal is to control symptoms, prevent and treat esophagitis and further complications.It includes lifestyle modifications, pharmacological therapy, endoluminal therapy, and surgical treatment with corrective surgery for preventing reflux.Laparoscopic Nissen fundoplication (LNF) is considered a gold standard surgical approach in the management of GERD. 1 There is a paucity of literature in India regarding comparison of health-related quality of life in LNF patients before and after the IntroductIonGastroesophageal reflux disease (GERD) is one of the most common chronic diseases of the gastrointestinal tract, characterized by the reflux of gastric contents to the esophagus, associated with typical and atypical esophageal symptoms including heartburn, regurgitation, epigastric abdominal pain, dysphagia, belching, abdominal bloating, coughing, wheezing, chronic sore throat, laryngitis, and asthma.If left untreated, it may lead to severe complications such as Barrett's esophagus, erosive esophagitis, and esophageal adenocarcinoma. 1,2he global age-standardized incidence of GERD was 3,793 per 100,000 population in 2019.The number of GERD cases increased by 77.53% from 1990 to 2019 (441.57 million to 783.95 million).Globally, GERD caused around 6.03 million people to live with disability, which corresponds to 73.63 age-standardized years lived with disability (ASYLDs) per 100,000 population in 2019.The highest prevalent cases were found in India (181.6 million), China (81.6 million), and the USA (39.7 million). 3,4The prevalence of GERD in India ranges from 5 to 28.5% (with one or more symptoms). 5here are many factors associated with GERD, which include hiatal hernia, transient lower esophageal sphincter relaxation, poor motor function, reduced clearance, increased intragastric pressure, delayed gastric emptying, age, obesity, diet, smoking, caffeine, alcohol, genetics, pregnancy, and nonsteroidal anti-inflammatory drugs. 6,7he overall quality of life in GERD patients is reduced as it creates multiple symptoms mentioned above, including sleep disturbance, 1,