Palladium-catalyzed synthesis creates quinolone derivatives from (hetero)arylamides, suggesting an efficient pathway.
A palladium-catalyzed strategy for the one pot synthesis of quinolone derivatives from (hetero)arylamides and functionalized 1,2-dihalobenzenes is described. The transformation likely proceeds through a Pd 1,4-migration from the amide nitrogen...
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Doucet et al. (2026) studied this question.
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