Multi-Route Administration Therapy for Intracranial Acinetobacter baumannii Infection After Postoperative Cerebral Hemorrhage: A Case Report

Objective: To explore the early diagnosis and treatment plan of intracranial infection with Acinetobacter baumannii . Methods: The clinical data of a patient with intracranial infection caused by Acinetobacter baumannii after intracranial hemorrhage surgery were analyzed. Combined with literature review, analyze the treatment plan for intracranial infection of Acinetobacter baumannii . Results: During the hospitalization of this patient, cerebrospinal fluid culture and routine biochemical monitoring were combined with procalcitonin and C-reactive protein for auxiliary diagnosis. The antibiotic treatment regimen was intravenous injection of meropenem and vancomycin, combined with artificial cerebrospinal fluid replacement and lumbar cisterior drainage. After one week of treatment, the patient’s condition improved and the bacterial culture of cerebrospinal fluid was negative. Conclusion: For intracranial infection caused by Acinetobacter baumannii , in this case, the patient was treated with meropenem + vancomycin via intravenous administration, combined with artificial cerebrospinal fluid replacement surgery + lumbar cistern drainage surgery. Although this treatment approach achieved relatively satisfactory therapeutic results, it is still a single-case empirical treatment. Due to the high rate of drug resistance and poor prognosis of intracranial Acinetobacter baumannii infection, there is currently no standardized unified treatment plan. More clinical studies are needed to accumulate data and further explore effective and with fewer adverse reactions treatment strategies to improve the clinical prognosis of such patients.