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June 18, 2026Asian Journal of Endoscopic Surgery

Preoperative Botulinum Toxin A Within an Endoscopic Retromuscular Strategy for Ventral Hernia Repair: A Preliminary Prospective Study in J apanese Patients

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Authors

KSKentaro ShinoharaTSTakuya SaitoKYKohei Yasui

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Overview

Prospective study showing botulinum toxin A aids endoscopic ventral hernia repair in Asian patients, suggesting effectiveness.

Key Points

  • This study aims to evaluate the effectiveness of preoperative botulinum toxin A in facilitating endoscopic retromuscular repair of ventral hernias.
  • Prospective, single-center study with 10 patients having midline ventral hernias ≥ 5 cm.
  • Ultrasound-guided injection of botulinum toxin A at weight-adjusted doses prior to surgery.
  • Surgical outcomes were evaluated post-operatively including CT scans.
  • Primary fascial closure achieved in all patients with no recurrence during a median follow-up of 12 months.
  • Median defect width decreased from 5.7 to 4.5 cm (p = 0.004).
  • No treatment-related adverse events occurred.

Cite This Study

Shinohara et al. (2026) studied this question.

synapsesocial.com/papers/6a338d85630953a74978e781https://doi.org/10.1111/ases.70323
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