Exploration reveals a new linker strategy for delivering hydroxyl-containing payloads in antibody-drug conjugates, suggesting advancements for next-gen therapies.
. Collectively, this work establishes a versatile and generalizable linker strategy that expands the accessible payload space of ADCs and enables efficient, controlled delivery of hydroxyl-containing payloads, highlighting its potential for next-generation ADC development.
No takes yet. Share an insight, caveat, or question.
Li et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: