Key result
Patients with Parkinson's disease exhibited significantly lower heart rate variability during a deep breathing test compared to healthy controls (12.53 vs 18.37 beats/min, p<0.05).
Why the study?
Does Parkinson's disease reduce heart rate variability during deep breathing compared to healthy controls?
Population
60 participants: 30 patients with Idiopathic Parkinson's disease without concomitant cardiovascular disease…
Comparison
3-minute deep breathing test to measure heart… vs Healthy age-matched controls undergoing the same…
Design
Case-control
Authors
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May flag early autonomic dysfunction in Parkinson's; hypothesis-generating for severity correlation, needs prospective validation before clinical use.
Case-Control (n=60)
No
Does Parkinson's disease reduce heart rate variability during deep breathing compared to healthy controls?
Absolute Event Rate: 12.53% vs 18.37%
p-value: p=<0.05
Parkinson's disease is associated with significantly reduced heart rate variability during deep breathing, indicating early parasympathetic autonomic dysfunction that correlates with disease severity.
Mukta P Bidikar (2014) conducted a case-control in Parkinson's disease (n=60). Parkinson's disease vs. Healthy age-matched controls was evaluated on Heart rate variability during deep breathing test (maximum-minimum heart rate in beats/min) (p=<0.05). Patients with Parkinson's disease exhibited significantly lower heart rate variability during a deep breathing test compared to healthy controls (12.53 vs 18.37 beats/min, p<0.05).
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