Abnormal heart rate turbulence (category 2) was a strong predictor of all-cause mortality in post-myocardial infarction patients (HR 5.9; 95% CI 2.9-12.2).
Cohort (n=1,455)
Does abnormal heart rate turbulence predict all-cause mortality in survivors of acute myocardial infarction?
Heart rate turbulence is a strong, independent predictor of all-cause mortality in post-myocardial infarction patients in the reperfusion era.
Hazard Ratio: 5.9 (95% CI 2.9–12.2)
BACKGROUND: Retrospective postinfarction studies revealed that decreased heart rate turbulence (HRT) indicates increased risk for subsequent death. This is the first prospective study to validate HRT in a large cohort of the reperfusion era. METHODS AND RESULTS: One thousand four hundred fifty-five survivors of an acute myocardial infarction (age or =65 years (2.4; 1.5 to 3.9), and HRT category 1 (2.4; 1.2 to 4.9). LVEF 30%, age > or =65 years, diabetes mellitus, and HRT category 2 had a sensitivity of 24% at a positive predictive accuracy level of 37%. The combined criteria of LVEF 30%, age > or =65 years, diabetes mellitus, and HRT category 1 or 2 had a sensitivity of 44% at a positive predictive accuracy level of 23%. CONCLUSIONS: HRT is a strong predictor of subsequent death in postinfarction patients of the reperfusion era.
Barthel et al. (Tue,) conducted a cohort in acute myocardial infarction (n=1,455). Heart rate turbulence (HRT) category 2 vs. Normal heart rate turbulence (HRT category 0) was evaluated on all-cause mortality (HR 5.9, 95% CI 2.9 to 12.2). Abnormal heart rate turbulence (category 2) was a strong predictor of all-cause mortality in post-myocardial infarction patients (HR 5.9; 95% CI 2.9-12.2).
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