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June 1, 2026HLA

Characterisation of the Novel HLA‐DRB4*01:229 Allele in a Korean Individual by Next‐Generation Sequencing

Jae Hee Lee You Hyun Jeon Dong Il Won

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Key Points

This research aims to characterize the novel HLA-DRB4*01:229 allele in a Korean individual.
Utilized next-generation sequencing for allele characterization.
Focused on identifying nucleotide substitutions in specific codons.
Analyzed genetic differences between HLA-DRB4*01:229 and HLA-DRB4*01:03:01:17.
Identified one nucleotide substitution in codon 156 of exon 3.
Confirmed the unique presence of the HLA-DRB4*01:229 allele in the individual.
Highlighted significant genetic variation in HLA-DRB4 alleles.

Implication

Genetic analysis characterizes a novel allele in a Korean individual, suggesting implications for genetic research.

Abstract

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Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/6a362ee4db0793dc1a5367ec https://doi.org/10.1111/tan.70811

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Characterisation of the Novel <i>HLA‐DQA1*04:29</i> Allele in a Korean Individual by Next‐Generation SequencingOriginal Research · 2026 · 1 citations
2Characterisation of the Novel HLA‐DRB3*01:127 Allele by Next‐Generation SequencingOriginal Research · 2026
3Characterisation of the Novel HLA‐DRB1*15:03:07 Allele by Next‐Generation SequencingOriginal Research · 2026
4Characterisation of the novel <i>HLA‐DRB4*01:182</i> allele by sequencing‐based typing2024 · 3 citations
5Characterisation of the novel <i>HLA‐DRB4*01:01:12</i> allele by sequencing‐based typing2024 · 3 citations

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