Systematic review shows higher liver uptake of PSMA-targeted PET imaging radiotracers, suggesting implications for therapy eligibility.
Higher liver background uptake was observed on prostate-specific membrane antigen (PSMA)–targeted PET imaging with fluorine 18 ( 18 F)-flotufolastat and 18 F-PSMA-1007 compared with 18 F-piflufolastat and gallium 68 ( 68 Ga)-PSMA-11, which may influence patient eligibility for PSMA-targeted therapy.
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Ulaner et al. (2026) studied this question.
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