Gaps in Patient-Facing Information on Artificial Intelligence in Cancer Care: A Cross-Sectional Analysis

PURPOSE Artificial intelligence (AI) is increasingly integrated into cancer care and accessible to patients, yet the quality and accessibility of patient-facing information on this topic are poorly characterized. We evaluated the quality, readability, and AI safety concept coverage of publicly available Webpages and YouTube videos that patients are likely to encounter when searching to learn about AI in cancer care. METHODS We conducted a cross-sectional analysis of digital content identified using Google Trends–derived search terms on August 6, 2025. Two independent reviewers screened the first 170 Google and 150 YouTube results for patient-facing content relevant to AI in cancer care, with discrepancies resolved by a third reviewer. Information quality was assessed using DISCERN (scale 1-5; ≥4 = high quality). Webpage readability was evaluated using Flesch-Kincaid (FK), Gunning Fog (GF), and Simplified Measure of Gobbledygook (SMOG) indices. Coverage of AI safety concepts (hallucination risk, clinician oversight, bias/equity, transparency) was assessed. RESULTS Of the 320 resources screened, 52 Webpages (31%) and 30 videos (20%) met inclusion criteria. Median DISCERN scores were 2.5 (IQR, 2.5-4.0) for Webpages and 2.25 (IQR, 1.5-3.0) for videos, indicating overall low-quality information. Only 17 Webpages (33%) and seven videos (23%) were of high quality. Median Webpage readability corresponded to college level across all indices (FK 12.5, GF 15.0, SMOG 14.3), exceeding the sixth- to eighth-grade reading level recommended by the American Medical Association and National Institutes of Health. Most Webpages addressed clinician oversight (79%) and transparency (79%), but few discussed hallucination risk (15%). CONCLUSION Patient-facing online information about AI in cancer care is limited, low in quality, difficult to read, and frequently omits safety concepts, highlighting an urgent need for accessible, high-quality resources.