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June 20, 2026JNCI Journal of the National Cancer Institute0 citations

Lung Cancer in Women: Present and Future Trends

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EWErnest L. WynderLCLirio S. CoveyKMKiyóhiko Mabuchi

Key Points

  • To examine the relationship between cigarette smoking and lung cancer types in women and assess future trends.
  • Retrospective analysis of 108 female lung cancer patients from 1970-72
  • Comparison of smoking intensity factors between 2213 female and 1839 male control patients
  • Assessment of smoking habits and lung cancer morbidity ratios
  • Cigarette smoking linked to epidermoid and oat-cell lung cancer types
  • Increased morbidity associated with higher smoking intensity, starting age, and inhalation practices
  • As women adopt male-like smoking habits, lung cancer death rates are expected to rise but remain below men's levels.

Abstract

Summary A retrospective study of 108 female lung-cancer patients seen during 1970-72 showed that cigarette smoking was closely associated with epidermoid and oat-cell types of lung cancer, and less strongly with glandular types of lung cancer. Among cigarette smokers of 1 pack/day, a longer history of smoking, earlier starting age, inhalation, and nonfilter cigarette smoking were significantly associated with greater lung-cancer morbidity ratios. Another study of 1839 male and 2213 female control patients showed great differences in various smoking-intensity factors between men and women, but the differences diminished at younger ages. As women adopt cigarette-smoking habits similar to those of men, the death rate from lung cancer in women will continue to increase. However, the level is not expected to attain that presently observed in men, since young women began smoking cigarettes with lower tar-yield (i.e., filters) than did men presently of lung-cancer age.

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Cite This Study

Wynder et al. (1973) studied this question.

synapsesocial.com/papers/6a3631a1db0793dc1a538808https://doi.org/10.1093/jnci/51.2.391
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