Assessing the impact of antimicrobial stewardship in low-income healthcare settings: a study of antibiotic use and antimicrobial susceptibility patterns in Indian hospitals
Randomized trial reports improved antibiotic compliance in Indian hospitals, implying effective antimicrobial stewardship strategies.
Key Points
The study aims to evaluate the effectiveness of a tailored antimicrobial stewardship initiative in combating antimicrobial resistance in Indian hospitals.
Implemented an antimicrobial stewardship surveillance program in 11 hospitals from January 2022 to June 2023.
Conducted training, compliance audits, and interventions from July 2022 to June 2023.
Followed the Model for Improvement methodology over an 18-month period.
Antibiotic compliance increased significantly from 10% to 71% across hospitals post-intervention.
Surgical prophylaxis compliance improved notably, especially in initially low-adherence hospitals.
Significant improvements in safer first-line antibiotic use with decreased reliance on second- and third-line antibiotics.