This study presents a novel approach for the development of biofunctional and skin-comfortable cotton textiles through the integration of blackcurrant water/ethanol pomace extract into polysaccharide-based fabric coating. Extraction of bioactive compounds from blackcurrant pomace was optimized using response surface methodology, yielding a total phenolic content of 36.04 mg GAE/g DW, along with significant contents of flavonoids (5.28 mg QE/g DW) and anthocyanins (5.18 mg/g DW). The cotton fabric was biofunctionalized using the layer-by-layer (LbL) deposition technique, incorporating blackcurrant pomace extract within four, eight, or twelve chitosan/pectin bilayers. The biofunctionalized fabrics exhibited no cytotoxic effect and demonstrated nearly 100% antioxidant and antibacterial activity against E. coli and S. aureus. Additionally, the LbL coating enabled tunable extract adsorption (0.09–2.70%) and stabilization of bioactive compounds on the cotton surface, resulting in adjustable fabric coloration and moisture management properties (assessed using the Moisture Management Tester). Molecular docking analysis provided insight into the interactions between HPLC-detected anthocyanins (cyanidin-3-O-glucoside, cyanidin-3-O-rutinoside, delphinidin-3-O-glucoside, and delphinidin-3-O-rutinoside) and polysaccharides, revealing an increase in binding affinity from cellulose to chitosan and pectin. The transition from comfort-oriented fabric to a material featuring integrated moisture management and enhanced biofunctionality, achieved by coating cotton with eight chitosan/pectin bilayers incorporating blackcurrant pomace extract, renders the textile suited for medical, protective, and high-comfort applications.
Ivanovska et al. (Thu,) studied this question.
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