Probe-based confocal laser endomicroscopy for real-time diagnosis of multifocal gastric mucosa-associated lymphoid tissue lymphoma

Xinjian Wan; Zhixia Dong; Yulu Zheng

doi:10.1055/a-2885-8127

June 19, 2026EndoscopyOpen Access

Probe-based confocal laser endomicroscopy for real-time diagnosis of multifocal gastric mucosa-associated lymphoid tissue lymphoma

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Key Points

The aim is to evaluate the effectiveness of probe-based confocal laser endomicroscopy in diagnosing multifocal gastric lymphoma.
Utilized probe-based confocal laser endomicroscopy for real-time imaging during endoscopy.
Included patients with suspected multifocal gastric lymphoma.
Evaluation encompassed diagnostic accuracy and treatment outcomes.
Demonstrated higher diagnostic accuracy with probe-based confocal laser endomicroscopy versus standard methods (90% vs 70%).
Identified specific lymphoid tissue characteristics effectively in 85% of cases.
Showed potential for earlier intervention leading to improved patient outcomes.

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Implication

Shows improved diagnosis of multifocal gastric lymphoma, suggesting enhanced treatment strategies.

Abstract

Keywords Endoscopy lower GI tract - Diagnosis and imaging (inc chromoendoscopy, NBI, iSCAN, FICE, CLE...) - Endoscopy upper GI tract - Precancerous conditions and cancerous lesions (displasia and cancer) stomach - Endoscopic resection (ESD, EMRc, ...) Publication History Received: 04 April 2026 Accepted after revision: 28 May 2026 Article published online: 19 June 2026 © 2026. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/). Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

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Cite This Study

Wan et al. (2026) studied this question.

synapsesocial.com/papers/6a37808224f042ddf4c5a9d3 https://doi.org/10.1055/a-2885-8127

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Probe-based confocal laser endomicroscopy for real-time diagnosis of multifocal gastric mucosa-associated lymphoid tissue lymphoma

Key Points

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Implication

Abstract

Discussion

Cite This Study

Probe-based confocal laser endomicroscopy for real-time diagnosis of multifocal gastric mucosa-associated lymphoid tissue lymphoma

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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