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Consensus recommendations guide appropriate use of sublobar resection in early-stage non-small cell lung cancer patients.
BACKGROUND: Two recent randomized clinical trials have shown sublobar resection to be non-inferior to lobectomy in node negative non-small cell lung cancer (NSCLC) <= 2cm. As a result, the utilization of sublobar resection in early lung cancer patients has significantly increased. Consensus recommendations are needed to guide its appropriate use. METHODS: The Society of Thoracic Surgeons Workforce on Evidence-Based Surgery assembled a panel of thoracic surgeons with clinical and methodological expertise to review the existing literature on this topic. A modified Delphi method, with parameters and thresholds determined a priori, was utilized until 75% agreement on the statements was reached. RESULTS: The panel identified 7 key areas of controversy. Three rounds of voting were required to reach >75% agreement on 21 statements to help guide appropriate utilization of sublobar resection in early-stage lung cancer. CONCLUSIONS: Despite results of recent randomized clinical trials, several key questions remain regarding sublobar resection for early-stage NSCLC. These statements will provide further guidance for clinicians considering the different surgical options.
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Khullar et al. (2026) studied this question.
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