A 12-week exercise intervention in chronic coronary syndrome patients yielded short-term improvements in light physical activity and cardiometabolic markers, but no long-term changes at 12 months.
Does a 12-week exercise intervention improve movement behaviors and cardiovascular risk factors in older adults with chronic coronary syndrome?
A 12-week exercise intervention in patients with chronic coronary syndrome produced short-term improvements in physical activity and cardiometabolic markers that were not sustained at 12 months.
ABSTRACT Physical activity (PA) is key to improve the prognosis of patients with chronic coronary syndrome (CCS). This study investigated changes in movement behaviors (MB), obesity markers, cardiorespiratory fitness (VO 2peak ), cardiometabolic risk (CMR), and brain‐derived neurotrophic factor (BDNF) and whether changes in MB are associated with VO 2peak , CMR, and BDNF from baseline to 9 months after a 12‐week exercise intervention. In total, 35 CCS patients ( M = 69.5 ± 6.4 years; 82.9% men) underwent a group‐based intervention; including two 1‐h exercise sessions per week Data was collected on anthropometrics, blood samples, cardiopulmonary exercise testing, and 7‐day accelerometry at baseline, 3‐month, and 12‐month follow‐up. Absolute changes were examined using paired t ‐tests. Mixed‐effects linear regression models were applied to investigate associations of MB with VO 2peak , CMR, and BDNF over time. Intra‐class correlations were calculated to estimate within‐person variability. From baseline to 3‐month follow‐up, light PA (23.7 min/d ± 10.9) increased and body mass index (−0.3 kg/m 2 ± 1.2), glucose (−0.8 mmol/L ± 0.3), and diastolic blood pressure (−2.7 mmHg ± 1.3) decreased. From baseline to 12‐month follow‐up, there were no changes in any marker. Regression models revealed no associations between any measure of habitual movement behaviors and VO 2peak , CMR, and BDNF over time. To conclude, short‐term but no long‐term changes in MB and cardiovascular health markers were observed among CCS patients after a 12‐week exercise intervention. Modeling the associations between MB and VO 2peak , CMR, and BDNF over time revealed considerable within‐person variability in the data, which should be considered in future research. Trial Registration NCT06178263, Retrospectively registered (20/12/2023)
Ullrich et al. (Sat,) conducted a other in chronic coronary syndrome (n=35). 12-week exercise intervention was evaluated on Changes in movement behaviors, obesity markers, cardiorespiratory fitness, cardiometabolic risk, and brain-derived neurotrophic factor. A 12-week exercise intervention in chronic coronary syndrome patients yielded short-term improvements in light physical activity and cardiometabolic markers, but no long-term changes at 12 months.