The controversial water memory experiment proposed by Jacques Benveniste in 1988 has never obtained a unified theoretical explanation in mainstream academia. Although mainstream double-blind experiments failed to reproduce the biological effect, numerous unresolved anomalies including thermal and magnetic erasure effects remain unexplained. Based on the PFUSRC topological ontology and Noetic-Affective dual-primordial framework, this paper puts forward a unified hypothesis: memory is a persistent topological anchoring structure across time, rather than an inherent attribute of material substances; water memory is only a special fluid-medium manifestation of this universal structural memory mechanism. This paper establishes a complete set of mathematical equations describing Noetic-Affective coupling, symmetry breaking, memory lifetime decay and structural disruption, quantitatively interpreting core experimental phenomena such as ultra-dilution paradox, narrow effective experimental window and poor replicability of blind trials. By cross-media isomorphism comparison among magnetized water, shape-memory alloys and slime mold path memory, this paper verifies that the same topological anchoring logic governs memory phenomena across solid, liquid and biological carriers. It further distinguishes the structural bias embedded in mainstream randomized double-blind experimental paradigms for topologically sensitive weak-coupling phenomena, provides falsifiable quantitative predictions and clear application boundaries for the structural memory model, and elevates the qualitative ontological interpretation of memory into a testable quantitative theoretical system.
Zhenmin Wang (2026) studied this question.