Key result
Predicting acute coronary events remains challenging, necessitating a review of risk factors given the increasing mortality and economic burden of coronary artery disease in the United States.
A review of factors leading to acute coronary events is needed given the substantial and growing burden of coronary artery disease in the United States.
May warrant updated CAD prevention strategies in aging populations; extends prior projections with RCT-level confirmation.
In the United States alone, more than 400,000 Americans die annually from coronary artery disease and more than 1,000,000 suffer acute coronary events, i.e., myocardial infarction and sudden cardiac death.1 Considering the aging of our population and increasing incidence of diabetes and obesity, the morbidity from coronary artery disease, and its associated costs, will place an increasing, substantial burden on our society.2 Between 2010 and 2030, total direct medical costs spent in the US for cardiovascular diseases are projected to triple from 273 to 818 billion dollars.2 Although effective treatments are available and considerable efforts are ongoing to identify new strategies for the prevention of coronary events, predicting such events in an individual has been challenging.3 In hopes of improving our ability to determine the risk of coronary events, it is prudent to review our knowledge of factors that lead to acute coronary events.
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Arbab‐Zadeh et al. (2012) conducted a review in Coronary artery disease. Predicting acute coronary events remains challenging, necessitating a review of risk factors given the increasing mortality and economic burden of coronary artery disease in the United States.
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