Key result
Coronary Sinus Reducer improves angina to CCS class I despite transient complete AV block.
Case Report (n=1)
No
This case presents the first report of acute transient complete AV block during Coronary Sinus Reducer implantation, highlighting the need for careful catheter manipulation and immediate temporary pacing availability in patients with baseline conduction disease or tortuous venous anatomy.
Transient AV block risk warrants temporary pacing readiness during CSR cannulation; first report leaves open true incidence in conduction disease.
Background and Clinical Significance: The Coronary Sinus Reducer (CSR) is a percutaneous therapeutic option for patients with refractory angina who are unsuitable for further myocardial revascularization. The procedure has a generally favorable safety profile, with a low rate of reported procedural complications. To our knowledge, major atrioventricular (AV) conduction disturbances during CSR implantation have not been previously described. This case highlights a rare but clinically relevant intraprocedural complication; Case Presentation: A 71-year-old man with multivessel coronary artery disease and previous coronary artery bypass grafting was referred for CSR implantation because of refractory angina despite optimal medical therapy and lack of further revascularization options. The procedure was performed via a right jugular venous approach. Baseline electrocardiography showed right bundle branch block and findings consistent with previous inferior myocardial infarction, without definite criteria for left anterior fascicular block. During coronary sinus cannulation, the patient developed transient complete AV block, resulting in an approximately 8–10-second ventricular pause without a stable ventricular escape rhythm. The conduction disturbance resolved after catheter withdrawal and repositioning. Given the severity of the event, a temporary transvenous pacemaker was inserted via the right femoral vein, allowing safe completion of CSR implantation. At three-month follow-up, angina had improved from Canadian Cardiovascular Society class III to class I, and no recurrent advanced AV block was documented; Conclusions: Transient complete AV block may occur during CSR implantation, particularly during coronary sinus manipulation and possibly in patients with pre-existing conduction disease. Careful catheter handling, prompt recognition of conduction disturbances, and immediate availability of temporary pacing support should be considered in selected high-risk patients undergoing CSR implantation.
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Pagnoni et al. (2026) conducted a case report in Refractory angina with multivessel coronary artery disease and baseline right bundle branch block (n=1). Coronary Sinus Reducer implantation with temporary transvenous pacemaker support was evaluated on Transient complete atrioventricular block during coronary sinus cannulation and angina symptom improvement at 3 months. Coronary Sinus Reducer implantation was complicated by a transient 8–10-second complete AV block during cannulation, but succeeded with temporary pacing and improved angina from CCS class III to I.
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