Key result
Low-gradient severe AS carries challenging clinical management with limited comparative outcome data vs high-gradient AS.
Cohort study reports clinical outcomes in discordant low-gradient versus high-gradient severe aortic stenosis, highlighting prognostic challenges in real-world patient care.
Patients with severe aortic stenosis (AS) and low transvalvular gradients represent a clinically challenging subgroup. Comparative real-world outcomes between low- and high-gradient severe AS remain limited.
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Darko et al. (2026) studied this question. Low-gradient severe aortic stenosis remains a clinically challenging subgroup with limited comparative real-world outcomes versus high-gradient severe aortic stenosis.
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