Key result
Serial 6MWT predicts heart failure mortality when modeled to account for non-linear individual trajectories.
Serial 6MWT may refine HF mortality prognostication; leaves open prospective validation of spline modeling before clinical adoption.
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Atias et al. (2026) conducted a letter in Heart failure. Serial six-minute walk testing was evaluated on Mortality. Serial six-minute walk testing provides prognostic value for mortality prediction in heart failure patients when modeled with spline-based flexibility to account for non-linear individual trajectories.
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